Companion Tools
Free calculators and checklists that go with Applied Drug Safety and Adverse Drug Reactions. Each one follows the scoring rules in the book and in the original publications, and works on phones, tablets and computers.
Causality assessment
Naranjo ADR Probability Scale
Ten questions that score how likely it is that a drug caused an adverse reaction.
Book: Appendix A.1WHO-UMC Causality Assessment
A guided walk through the WHO-UMC criteria to a suggested causality category.
Book: Appendix A.2RUCAM Calculator (2016 update)
Scores suspected drug-induced liver injury on the hepatocellular or cholestatic/mixed worksheet.
Book: Appendix A.3 and Chapter 2Causality Assessment Record
A printable form to document the assessment, the tools used and your rationale.
Book: Appendix A.5
Organ-specific tools
Liver Injury Pattern and Hy's Law
Works out the R ratio, the injury pattern, the RUCAM worksheet to use and Hy's Law.
Book: Chapter 2Drug-Induced AKI: KDIGO Stage and Risk Factors
Stages acute kidney injury and lists the risk modifiers described in the book.
Book: Chapter 3SCORTEN for SJS/TEN
Seven admission criteria and the predicted hospital mortality for SJS/TEN.
Book: Chapter 5
Pharmacovigilance
ICSR Quality Checklist
Checks a case report for the four minimum elements and the details that make it useful.
Book: Chapter 16Disproportionality Calculator (PRR and ROR)
PRR, ROR, confidence intervals and chi-squared from a 2x2 table of reports.
Book: Chapter 16